Endocrine Pancreatic Insufficiency in Cystic Fibrosis: An Update

Registration Statement

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View Agenda  Hilton Chicago ChicagoIL Thursday
Sep 8, 2011 6:00 AM


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Program Description

Successful management of gastrointestinal (GI) complications in patients with cystic fibrosis (CF) is essential to maintain good health. Orally administered pancreatic enzyme replacement therapy (PERT) is the treatment of choice to improve impaired nutritional status due to exocrine pancreatic insufficiency (EPI) in patients with CF. Unfortunately, this strategy is associated with a varying level of success, as pill burden leads to low adherence and seriously impedes positive patient outcomes. If left untreated, EPI leads to a reduction in fat and protein absorption to dramatically low levels, placing patients at risk of malnutrition and poor growth resulting in premature death. It is well established that nutrition and lung function are closely linked in CF. As the life expectancy of CF patients increases, the clinical challenges experienced in pediatric populations are expected to extend into the management of adult CF patients.


Through this clinical update designed to increase understanding of the management challenges and mechanisms, symptoms, and treatments surrounding CF, as well as to improve the clinical application of this knowledge, clinicians will be able to enhance the treatment of their patients with CF.


This program is not affiliated with Digestive Disease Week.


Peter R. Durie, MD, FRCPC (chair)
Professor, Department of Pediatrics
University of Toronto
Senior Scientist
Research Institute
The Hospital for Sick Children
Toronto, Canada

Virginia A. Stallings, MD
Director, Nutrition Center
Jean A. Cortner Endowed Chair in Gastroenterology and Nutrition
The Children’s Hospital of Philadelphia
Philadelphia, PA

Target Audience

This activity is intended for physicians involved in the management of patients with cystic fibrosis.

Educational Objectives

This program is designed to address the following IOM competencies: provide patient-centered care and employ evidence-based practice.

At the conclusion of this activity, participants should be able to demonstrate the ability to:

  • Explain the relationship between exocrine pancreatic insufficiency (EPI) for survival and quality of life in cystic fibrosis
  • Recognize the pathophysiology, symptoms, and diagnosis of EPI and understand the consequences if the complication is not appropriately managed
  • Explain and differentiate the importance and validation of pancreatic function testing in the clinical evaluation and management of EPI
  • Recognize the barriers to the management of EPI and understand the need for new modalities that address these barriers


This activity has been planned and implemented in accordance with the Essential Areas and policies of the Accreditation Council for Continuing Medical Education through the joint sponsorship of Potomac Center for Medical Education and Rockpointe Corporation. Potomac Center for Medical Education is accredited by the ACCME to provide continuing medical education for physicians.

Designation Statement

Potomac Center for Medical Education designates this educational activity for a maximum of 1.5 AMA PRA Category 1 Credit(s)TM. Physicians should only claim credit commensurate with the extent of their participation in the activity.

For questions regarding CME credit, the post-test, or evaluation, please email contact@potomacme.org

Disclosure Information

Potomac Center for Medical Education (PCME) adheres to the policies and guidelines, including the Standards for Commercial Support, set forth to providers by the Accreditation Council for Con¬tinuing Medical Education (ACCME) and all other professional organizations, as applicable, stating those activities where continuing education credits are awarded must be balanced, independent, objective, and scientifically rigorous.

All persons in a position to control the content of a continuing medical education program sponsored by the Potomac Center for Medical Education are required to disclose any relevant financial relation-ships with any commercial interest to PCME as well as to learners. All conflicts are identified and resolved by PCME in accordance with the Standards for Commercial Support in advance of delivery of the activity to learners. Disclosures will be made known to the participants prior to the activity.

The content of this activity was vetted by an external medical reviewer to assure objectivity and that the activity is free of commercial bias.


To complete this activity and receive credit, the participant must attend the program, and complete the evaluation form. A CME certificate will be mailed within 6-8 weeks.

There are no fees associated with this program.


Event staff will be glad to assist you with any special needs (e.g. physical, dietary, etc.). Please email specialservices@potomacme.org at least 5 days prior to the program.

Jointly Sponsored By


Supported By

Supported by an educational grant from: Lilly USA, LLC


View Agenda  Hilton Chicago ChicagoIL Thursday
Sep 8, 2011 6:00 AM