This program will examine several seemingly unrelated, complicated disease states and explore common underlying pathologic features that confer increased risk of major adverse cardiovascular events. Diseases such as complex dyslipidemia, diabetes mellitus, and chronic kidney disease all commonly lead to adverse clinical events that reflect underlying cardiovascular disease. As such, this webcourse describes the inter-relationships of pathologic processes that converge and manifest as cardiovascular risk elements.
Complex Cardiovascular Cases will inform physicians about the latest clinical data and new therapeutic insights regarding treatment options to reduce the risk of major adverse cardiac events in patients with a variety of complex disease states. It will also provide physicians with the latest informed thinking about how to incorporate new therapeutic insights into clinical practice, in order to reduce risk of major adverse cardiovascular events in their at-risk patients.
Cases presented by:
DANA SIMPLER, MD
Primary Care Practitioner, Internal Medicine
Mercy Medical Center
Dr. Simpler deals with complex cardiovascular cases on a daily basis as an internist at Mercy Medical Center in Baltimore, MD.
MICHAEL H. DAVIDSON, MD, FACC, FACP, FNLA (Chair)
Director of Preventive Cardiology
The University of Chicago Pritzker School of Medicine
Michael H. Davidson, MD, FACC, FACP, FNLA is Clinical Professor and Director of Preventive Cardiology at the University of Chicago. He also serves as Consulting CMO for Omthera Pharmaceuticals. Dr. Davidson earned his medical degree from The Ohio State University College of Medicine in Columbus. He then completed his residency and fellowship in cardiology at Rush University Medical Center in Chicago.
An active researcher, Dr. Davidson’s clinical research background encompasses both pharmaceutical and nutritional clinical trials. His extensive research on statins, novel lipid-lowering drugs, and non-pharmacologic risk factor reduction has established him as a key opinion leader in this area. A prolific author and lecturer on lipid disorders, nutrition, and atherosclerosis, Dr. Davidson has coordinated more than 1,000 clinical trials in areas of preventive cardiology, published more than 250 articles for leading medical journals, and written 3 books on lipidology.
Dr. Davidson is board-certified in internal medicine, cardiology, and clinical lipidology. He is a Fellow of the American College of Cardiology and the American College of Chest Physicians. In addition, he is President (2010-2011) of the National Lipid Association. He was named in The Best Doctors in America for the past 10 years and was named Father of the Year by the American Diabetes Association in 2010.
GEORGE BAKRIS, MD, DMSc (Hon.), FASH, FASN
Professor of Medicine
Director, Hypertensive Diseases Unit
The University of Chicago Pritzker School of Medicine
George Bakris, MD, DMSc (Hon.), FASH, FASN received his medical degree from the Chicago Medical School and completed a residency in internal medicine at the Mayo Graduate School of Medicine, where he also completed a research fellowship in physiology and biophysics. He then completed fellowships in nephrology and clinical pharmacology at the University of Chicago. From 1988 to 1991, he served as Director of Renal Research at the Ochsner Clinic and on the faculty in the Departments of Medicine and Physiology at Tulane University School of Medicine. He later was Professor and Vice Chairman of Preventive Medicine and Director of the Rush University Hypertension Center in Chicago from 1993 until 2006. Currently, he is a Professor of Medicine and Director of the Hypertensive Diseases Unit in the Department of Medicine at the University of Chicago, Pritzker School of Medicine.
Dr. Bakris has published more than 500 articles and book chapters in the areas of diabetic kidney disease, hypertension, and progression of nephropathy. He is the Editor or Co-editor of 8 books in the areas of kidney disease progression and diabetes. In addition, he is the Associate Editor of the International Textbook of Cardiology. He was a member of the NIH National High Blood Pressure Education Program Working Group on Hypertension and Renal Disease, and served as an expert-consultant to the Cardio-renal Advisory Board of the FDA. He chaired the first National Kidney Foundation Consensus report on blood pressure and impact on renal disease progression, and has also served on many national guideline committees. Dr. Bakris is also the Past-president of the American College of Clinical Pharmacology and the current President of the American Society of Hypertension (ASH). He is the current Editor of American Journal of Nephrology and serves on more than 14 editorial boards, including Kidney International, Nephrology, Dialysis & Transplant, Hypertension, Journal of Hypertension, and Journal of the American Society of Hypertension.
MATTHEW R. WEIR, MD
Professor and Director
Division of Nephrology
University of Maryland School of Medicine
Matthew R. Weir, MD is attending physician and Director of the Division of Nephrology in the Department of Medicine at the University of Maryland Hospital, Baltimore, MD. He is also Professor of Medicine at the University of Maryland School of Medicine.
Dr. Weir’s primary research interests include the use of antihypertensive therapy for the treatment of diabetic nephropathy, hypertensive renal injury in African Americans, and preventing allograft nephropathy in transplant recipients. He has written more than 450 manuscripts and book chapters about these topics. He has edited 4 books, including Medical Management of Kidney Transplantation and Hypertension. He has presented at numerous international scientific association meetings, hospitals, and medical schools.
Dr. Weir currently reviews manuscripts for more than 20 major medical journals, including the American Journal of Kidney Disease, Journal of the American Society of Nephrology, and Archives of Internal Medicine. He is on the editorial board of 10 journals and is Associate Editor of Clinical Nephrology and the American Journal of Nephrology. In addition, he is a member of numerous associations, including the American Society of Nephrology, the National Kidney Foundation, the American Heart Association, and the American Society of Transplantation.
Dr. Weir received his medical degree from the University of Virginia, Charlottesville. He completed his internship and residency programs in medicine at the Waterbury and Yale-New Haven Hospitals in Connecticut, and completed his nephrology training at the Brigham and Women’s Hospital, Harvard Medical School, in Boston, MA. He then moved to the University of Maryland where he has been a full-time faculty member since 1983.
This activity is intended for cardiologists and other physicians who manage patients with complex cardiovascular risk.
This program is designed to address the following IOM competencies: provide patient-centered care and employ evidence-based practice.
At the conclusion of this activity, participants should be able to demonstrate improved ability to:
- Examine the relative effectiveness of intensive statin treatment and existing HDL raising therapies to reduce CVD risk in dyslipidemic patients
- Explain the clinical data that illustrate the effectiveness of renin system modulation and lipoprotein management to reduce CVD risk in patients with chronic kidney disease
- Discuss the complexities of reducing CVD risk in patients with diabetes mellitus
- Incorporate multifaceted CVD risk factor reduction strategies into the management of patients with complicated health issues that put them at risk of major adverse cardiovascular events
This activity has been planned and implemented in accordance with the Essential Areas and policies of the Accreditation Council for Continuing Medical Education through the joint sponsorship of the Potomac Center for Medical Education and Rockpointe Corporation. The Potomac Center for Medical Education is accredited by the ACCME to provide continuing medical education for physicians.
The Potomac Center for Medical Education designates this educational activity for a maximum of 1.5 AMA PRA Category 1 Credit(s)™. Physicians should only claim credit commensurate with the extent of their participation in the activity.
For questions regarding CME credit, the post-test, or evaluation, please email firstname.lastname@example.org.
The Potomac Center for Medical Education (PCME) adheres to the policies and guidelines, including the Standards for Commercial Support, set forth to providers by the Accreditation Council for Continuing Medical Education (ACCME) and all other professional organizations, as applicable, stating those activities where continuing education credits are awarded must be balanced, independent, objective, and scientifically rigorous.
All persons in a position to control the content of a continuing medical education program sponsored by the Potomac Center for Medical Education are required to disclose any relevant financial relationships with any commercial interest to PCME as well as to learners. All conflicts are identified and resolved by PCME in accordance with the Standards for Commercial Support in advance of delivery of the activity to learners. Disclosures will be made known to the participants prior to the activity.
The content of this activity was vetted by an external medical reviewer to assure objectivity and that the activity is free of commercial bias.
The faculty reported the following relevant financial relationships that they or their spouse/partner have with commercial interests:
Michael H. Davidson, MD, FACC, FACP, FNLA: Advisory Board/Consultant:: Amgen, Merck & Co., Roche, Sanofi-Aventis; Board of Directors/Equity: Omthera Pharmaceuticals
George Bakris, MD, DMSc (Hon.), FASH, FASN: Research Support:: Forest Labs, Novartis; Principal Investigator: Medtronic, Relapysa; Consultant: Abbott, CVRx, Eli Lilly, Food and Drug Administration, Johnson & Johnson, Servier, Takeda; Speakers Bureau: Novartis, Takeda
Matthew R. Weir, MD: Scientific Consultant: Merck & Co., Novartis, Pfizer, Sanofi
Dana Simpler, MD: Nothing to Disclose
Non-faculty content contributors and/or reviewers reported the following relevant financial relationships that they or their spouse/partner have with commercial interests:
Barry Watkins, PhD; Bradley Pine; Blair St. Amand; Jay Katz; Laurie Frueh, MD: Nothing to Disclose
The contents of some CME activities may contain discussions of non-approved or off-label uses of some agents mentioned. Please consult the prescribing information for full disclosure of approved uses.
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Instructions for Participants and Obtaining CME Credit
There is no fee for this activity. To receive credit, participants must take the pre-test, view this CME activity in its entirety, and then complete the post-test and evaluation. To complete the evaluation online, choose the best answer to each question. The estimated time for completion of this activity is 1.5 hours. To receive their certificates, participants must demonstrate mastery of the presented material via the post-test.
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