The Advancing Science of MS Management: Optimizing DMD Therapy

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Release Date: Jul 11, 2014          Expiration Date: Jul 11, 2015

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Program Description

The diagnosis and management of multiple sclerosis (MS) continue to evolve with the rapid emergence of new agents, new diagnostic criteria, and the identification of MRI measures and biomarkers capable of improving disease surveillance. Combined with the continued push for earlier diagnosis and initiation of disease-modifying drug therapy (DMD), MS diagnosis and management is becoming increasingly complex. Clinicians face more treatment choices, making the formulation of optimal DMD therapies increasingly difficult. In addition, patient concerns with DMD side effects, treatment preferences, drug costs, and other issues continue to negatively impact patient acceptance of and adherence to DMD treatments.

This program will review the latest research and clinical management information on DMD therapies, diagnostic MRI measures, and biomarkers, in order to provide neurologists and other MS specialists with the knowledge and skills needed to improve the management and outcomes of patients with MS.


Download (PDF) Click here to download the program slides from the live meeting held May 28, 2014 at the Hilton Anatole, Dallas, TX, during the 2014 Cooperative Meeting of the Consortium of MS Centers (CMSC) and the Americas Committee for Treatment and Research in MS (ACTRIMS).


Suhayl Dhib-Jalbut, MD
Professor and Chairman
Department of Neurology
Rutgers-Robert Wood Johnson Medical School
Chief, Neurology Service
Robert Wood Johnson University Hospital
New Brunswick, NJ

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Clyde E. Markowitz, MD
Chief, MS Section
Director, MS Center
Associate Professor of Neurology
Perelman School of Medicine
University of Pennsylvania
Philadelphia, PA

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Aaron E. Miller, MD
Professor of Neurology
Medical Director, The Corinne Goldsmith Dickinson Center for Multiple Sclerosis
Mount Sinai Medical Center
New York, NY

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Target Audience

This activity is intended for MS specialists, neurologists, and other health care professionals who manage patients with MS.

Educational Objectives

At the conclusion of this activity, participants should be able to demonstrate the ability to:

  • Employ newer MRI criteria to improve the early diagnosis of MS
  • Select effective DMD therapies earlier in the course of MS
  • Describe the mechanisms of action and efficacy and safety profiles of current and emerging DMD therapies in MS
  • Develop patient-tailored therapies that optimize adherence, increase effectiveness, and improve individual patient outcomes
  • Apply evidence from recent diagnostic and prognostic biomarker studies to improve the monitoring of disease activity and response to DMD therapy in MS


Physicians – This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of the Potomac Center for Medical Education and Rockpointe. The Potomac Center for Medical Education is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

Nurses – Global Education Group is accredited as a provider of continuing nursing education by the American Nurses Credentialing Center's Commission on Accreditation.

Designation Statement

Physicians – The Potomac Center for Medical Education designates this live activity for a maximum of 1.25 AMA PRA Category 1 credit(s)™. Physicians should only claim credit commensurate with the extent of their participation in the activity.

For questions regarding CME credit, the post-test, evaluation, please email

Nurses – This educational activity for 1.25 contact hours is provided by Global Education Group. For information about the nursing accreditation of this program, please contact Global at or 303-395-1782.


Potomac Center for Medical Education (PCME) adheres to the policies and guidelines, including the Standards for Commercial Support, set forth to providers by the Accreditation Council for Continuing Medical Education (ACCME) and all other professional organizations, as applicable, stating those activities where continuing education credits are awarded must be balanced, independent, objective, and scientifically rigorous.

All persons in a position to control the content of a continuing medical education program provided by PCME are required to disclose any relevant financial relationships with any commercial interest to PCME as well as to learners. All conflicts are identified and resolved by PCME in accordance with the Standards for Commercial Support in advance of delivery of the activity to learners.

The content of this activity was vetted by an external medical reviewer to assure objectivity and that the activity is free of commercial bias.

The faculty and steering committee reported the following relevant financial relationships that they or their spouse/partner have with commercial interests:

Suhayl Dhib-Jalbut, MD: Consultant: AbbVie, Bayer, Novartis, Serono, Teva; Grant Support: Novartis, Teva

Clyde E. Markowitz, MD: Consultant: Bayer Healthcare, Biogen Idec, EMD Serono, Genentech, Genzyme, Novartis, Roche, Teva

Aaron E. Miller, MD: Consultant: Acorda Therapeutics, Accordant Health Services (Caremark), Biogen Idec, EMD Serono, Genzyme/Sanofi-Aventis, GlaxoSmithKline, Novartis, Nuron Biotech; Research Support: Acorda Therapeutics, Biogen Idec, Genentech, Genzyme/Sanofi-Aventis, Novartis, Roche, Questcor

Non-faculty Disclosures
Non-faculty content contributors and/or reviewers reported the following relevant financial relationships that they or their spouse/partner have with commercial interests:

Matthew Horn, MD; Blair St. Amand; Jay Katz, CCMEP; Amanda Glazar, PhD; Ashley Marostica, MSN, RN; Dana Simpler, MD: Nothing to disclose

FDA Disclosure

The contents of some CME/CE activities may contain discussions of non-approved or off-label uses of some agents mentioned. Please consult the prescribing information for full disclosure of approved uses.

System Requirements

In order to view this presentation, your computer must have audio capabilities (working speakers or headphones) and must have an Adobe Flash Player. The Adobe Flash Player can be downloaded here.


There is no fee for this activity. To receive credit, participants must take the pre-test, view this CME activity in its entirety, and then complete the post-test and evaluation. To complete the evaluation online, choose the best answer to each question. The estimated time for completion of this activity is 1.0 hour. To receive their certificates, participants must demonstrate mastery of the presented material via the post-test by obtaining a score of 71%. Participant is allowed to take the post-test three times.


Potomac Center for Medical Education and Rockpointe


Global Education Group

Supported By

This activity is supported by an educational grant from Teva Neuroscience.

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