New Insights into Managing HIV-1:

Guideline Recommendations, Individualized Treatment, and Management of Comorbidities

A series of Live Grand Rounds Programs and an on-demand CME-certified Webcourse.

Welcome to "New Insights into Managing HIV-1: Guideline Recommendations, Individualized Treatment, and Management of Comorbidities." This CME-certified initiative has a target audience of infectious disease specialists, internists, Primary Care Physicians , and family practitioners. A series of live CME-certified programs will be presented at selected hospitals throughout the US during 2014/2015, and an online CME-certified webcourse will also be available.

Program Overview/Statement of Need:

With the development of more effective and better tolerated therapies for HIV-1 infection, patients are living longer with the disease. There is high and comparable efficacy among many of the treatment regimens for HIV-1, but they vary in regard to pill burden, dosing frequency, potential long- and short-term side effects, barriers to resistance, and drug interactions. Treatment for patients with HIV-1 must be individualized and choice is based on convenience, side-effect profile, known or suspected resistance, and interactions with concomitant medications, along with the presence or absence of comorbidities such as cardiovascular disease, renal dysfunction, psychiatric illness, and substance-use history.

New Insights into Managing HIV-1 will review the recent updates to the guidelines for the management of HIV-1 infection and present new data on the efficacy/tolerability profiles of various treatment regimens to enhance patient care and optimize overall outcomes.

Accreditation Statements:

This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of the Potomac Center for Medical Education and Rockpointe. The Potomac Center for Medical Education is accredited by the ACCME to provide continuing medical education for physicians.

Physician Credit Designation:

The Potomac Center for Medical Education designates this live activity for a maximum of 1.0 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

For information about the accreditation of this program, please email contact@rockpointe-pcme.com.

Disclosure of Conflicts of Interest:

PCME requires instructors, planners, managers and other individuals and their spouse/life partner who are in a position to control the content of this activity to disclose any real or apparent conflict of interest they may have as related to the content of this activity. All identified conflicts of interest are thoroughly vetted by Global for fair balance, scientific objectivity of studies mentioned in the materials or used as the basis for content, and appropriateness of patient care recommendations.

Calendars for Live Activities

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Visiting Professor Series

Related Online Offerings

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Click here to view the webcourse which was adapted from the curriculum developed and presented for this series of CME-certified grand rounds.

Live Program Materials for Speakers and Administrators

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I. Administrator Material

II. Speaker Material

Audio Orientation

Thank you for joining us as an expert speaker for the Visiting Professor Series, "New Insights into Managing HIV-1: Guideline Recommendations, Individualized Treatment, and Management of Comorbidities."

This orientation will familiarize you with the complete slide set, provide insight from the program steering committee, and address potential questions. During the audio lecture, the following key topics will be discussed:

  • Integrate recent clinical trial data into updated HIV management guidelines to provide the most individualized treatment for HIV-1-infected patients
  • Develop a patient-centered approach to individualizing treatment for HIV by minimizing short- and long-term treatment-related complications
  • Incorporate considerations about a patient's risks for adverse events, non-adherence, and comorbid conditions when individualizing HIV treatments

Transcript of Speaker Orientation Download (PDF)

Audio download of Speaker Orientation
Audio Download

CME-certified Program Slides

This version of the program slides has been CME-certified and these slides are to be used for this activity. Download (PowerPoint)

Steering Committee and Speaker Biographies

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FLAVIO VINCENTI, MDRAPHAEL J. LANDOVITZ, MD, MSc
Associate Professor of Medicine
Division of Infectious Diseases
Center for Clinical AIDS Research and Education
David Geffen School of Medicine
Los Angeles, CA


Raphael J. Landovitz, MD, MSc completed his education and medical training at Princeton University, Harvard Medical School, Brigham and Women's Hospital, and Massachusetts General Hospital. He is the Medical Co-director of the Vietnam-CDC-Harvard Medical School-AIDS-Partnership (VCHAP), helping to train Vietnamese physicians in HIV care and treatment.

Dr. Landovitz relocated to Los Angeles in 2006, and is an Associate Professor of Medicine at the UCLA Center for Clinical AIDS Research and Education. Funded by the National Institutes of Health (NIH), California HIV Research Program (CHRP), and the state, county, and city of Los Angeles, he has led combination prevention/intervention studies and projects using post-exposure (PEP) and pre-exposure (PrEP) strategies for homosexual men, transgender women, and cis-gender women, as well as being part of leadership groups of the DAIDS-funded AIDS Clinical Trials Group (ACTG), HIV Prevention Trials Network (HPTN), and the Adolescent Trials Network (ATN).

He is the Principal Investigator of a multisite PrEP demonstration project in Los Angeles County, and the Study Chair of a Phase II study of long-acting injectable PrEP. His research agenda focuses on the optimization of the use of antiretroviral medications for both HIV treatment and HIV prevention. He was awarded the John Carey Young Investigator Award by the ACTG in 2010.


ROY D. BLOOM, MDPAUL SAX, MD
Clinical Director, Division of Infectious Diseases
Brigham and Women's Hospital
Professor of Medicine
Harvard Medical School
Boston, MA


Paul Sax, MD is Clinical Director of the Division of Infectious Diseases and the HIV Program at Brigham and Women's Hospital (BWH), and Professor of Medicine at Harvard Medical School. Dr. Sax received his medical doctorate from Harvard Medical School in 1987. He served his residency in internal medicine at BWH, while continuing his postdoctoral education with a fellowship in the Infectious Disease Unit of Massachusetts General Hospital.

Dr. Sax is board-certified in internal medicine and infectious diseases. He is Editor-in-Chief of Open Forum Infectious Diseases, serves on the Peer Review Board of the HIV/AIDS Section of UpToDate, and is on the Editorial Advisory Board of Medscape HIV/AIDS. Dr. Sax is also on the core faculty of the International AIDS Society-USA and the New England AIDS Education and Training Center. In addition to his clinical and teaching work, Dr. Sax's ongoing areas of research include clinical trials of antiretroviral therapies, cost-effectiveness of management strategies for HIV, and toxicity of antiretroviral therapy. He is presently the Principal Investigator at the BWH AIDS Clinical Trials Unit, and is a member of the Cost-Effectiveness of Preventing AIDS Complications (CEPAC) Research Group.

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JOINTLY PROVIDED BY

Jointly provided by Potomac Center for Medical Education and Rockpointe.

SUPPORTED BY

Supported by an educational grant from Merck.
©2014 Rockpointe