Neurology Exchange: Integrating New DMD Therapies Into the MS Treatment Landscape

A series of Live Grand Rounds Programs and an On-demand Webcourse

Welcome to "Integrating New DMD Therapies Into the MS Treatment Landscape.” This CME-certified initiative is intended for MS specialists, neurologists, PCPs, and other health care professionals who manage patients with MS. A series of live CME-certified programs will be presented at selected hospitals and an online CME-certified webcourse will be available in Spring 2016.

Program Description

The diagnosis and management of multiple sclerosis (MS) continue to rapidly evolve, with an ongoing emergence of new disease-modifying agents; newer diagnostic criteria and revisions to MS phenotypes; and the identification of MRI measures and biomarkers capable of improving disease surveillance. Combined with the continued push for earlier diagnosis and initiation of disease-modifying drug (DMD) therapy, MS diagnosis and management continues to become more challenging.

Clinicians face more treatment choices and must address patient concerns about DMD side effects, treatment preferences, drug costs, and other issues that can negatively impact acceptance of and adherence to DMD treatments. Improved patient engagement and patient-centered care, as well as more comprehensive management of treatment-related side effects and common comorbidities, are increasingly important areas of focus in MS care.

Integrating New DMD Therapies into the MS Treatment Landscape will provide clinicians with the latest information on patient engagement and recent advances in MS diagnosis and management, in order to optimize outcomes for their patients with MS.

Learning Objectives:

At the conclusion of this activity, participants should be able to demonstrate the ability to:

  • Explain the mechanisms of action, efficacy, and safety profiles of current and emerging DMD therapies in MS
  • Identify evidence-based, patient-tailored therapeutic principles for early therapy initiation and monitoring
  • Outline barriers to DMD treatment adherence and effective responses
  • Review modifiable risk factors and ongoing evaluations to improve MS care, as well as programs to manage common treatment-related side effects
Accreditation Statements:

This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of the Potomac Center for Medical Education and Rockpointe. The Potomac Center for Medical Education is accredited by the ACCME to provide continuing medical education for physicians.

Designation Statements:

Physicians - The Potomac Center for Medical Education designates this live activity for a maximum of 1.0 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

For information about the accreditation of this program, please email contact@potomacme.org.

Physician Assistants - The American Academy of Physician Assistants accepts certificates of participation for educational activities certified for AMA PRA Category 1 Credit™ from organizations accredited by the ACCME or a recognized state medical society. Physician assistants may receive a maximum of 1.0 hours of Category I credit for completing this program.

Nurse Practitioners - The American Academy of Nurse Practitioners accepts certificates of participation for educational activities certified for AMA PRA Category 1 Credit™ from organizations accredited by the ACCME or a recognized state medical society. Nurse practitioners (and CNMs) may receive a maximum of 1.0 hours of Category I credit for completing this program.

Calendar for Live Activities

If you are interested in attending a meeting in your local area, please contact Alexis Haley at 443-909-7907 or cbeavan@rockpointe.com for the schedule.

Calendar for Live Activities

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Related Online Offerings

Click here to access the CME-certified webcourse associated with this program. (Coming soon)

Live Program Materials for Speakers and Administrators

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I. Administrator Material

II. Speaker Material

Audio Orientation

Thank you for joining us as an expert speaker for the 2016 Grand Rounds series, “Integrating New DMD Therapies into the MS Treatment Landscape." This orientation will familiarize you with the complete slide set, provide insight from the program steering committee, and address potential questions. During the audio lecture, the following key topics will be discussed:

  • Mechanisms of action and efficacy and safety profiles of current and emerging DMD therapies in MS
  • Evidence-based, patient-tailored therapeutic principles for early therapy initiation and monitoring
  • Barriers to DMD treatment adherence and effective responses
  • Modifiable risk factors and ongoing evaluations to improve MS care, as well as programs to manage common treatment-related side effects

Transcript of Speaker Orientation Download (PDF) [Coming Soon]

Transcript of Speaker Orientation Download (PDF)

Audio download of Speaker Orientation Audio [Coming Soon]

Audio download of Speaker Orientation

Audio Download

CME-certified Program Slides

This version of the program slides has been CME-certified and these slides are to be used for this activity. Download (PowerPoint) [Coming Soon]

This version of the program slides has been CME-certified and these slides are to be used for this activity. Download (PDF)

Steering Committee Biographies

All steering committee and speaking faculty disclosures will be provided onsite in program syllabi distributed to all grand rounds participants.

Patricia K. Coyle, MD, FAAN, FANA Patricia K. Coyle, MD, FAAN, FANA

Professor and Vice Chair (Clinical Affairs)
Department of Neurology
Director, MS Comprehensive Care Center
Stony Brook University Medical Center
Stony Brook, NY

Patricia K. Coyle, MD, FAAN, FANA is Professor and Vice Chair (Clinical Affairs) of Neurology and Director of the Multiple Sclerosis Comprehensive Care Center at Stony Brook University Medical Center in Stony Brook, NY. She earned her bachelor of science degree with highest honors from Fordham University in the Bronx, NY and a medical doctorate from the Johns Hopkins School of Medicine, where she was elected to Alpha Omega Alpha. While at the Johns Hopkins School of Medicine, she completed a residency and chief residency in neurology, followed by a two-year fellowship in neuroimmunology and neurovirology. She then went on to establish a successful research laboratory in addition to building a busy clinical practice at the Stony Brook University Medical Center.

Dr. Coyle is the author of numerous articles on clinical and basic research aspects of multiple sclerosis (MS) and neurologic infections and she is recognized as a leading expert in these areas. Other areas of expertise include Lyme disease, cerebrospinal fluid, therapeutics, and neuroimmunology. Her research has been supported by the National Institutes of Health and other organizations. She is currently involved in a number of therapeutic trials testing new immunotherapies for MS, as well as studies addressing neurologic aspects of Lyme disease. In addition to her busy clinical and research careers, she has held active leadership positions in a number of national and international organizations and academic societies, including the American Academy of Neurology, American Neurological Association, National MS Society, and the American Board of Psychiatry and Neurology. She lectures widely on MS and neurologic infections to national and international audiences.

Clyde E. Markowitz, MD Clyde E. Markowitz, MD

Chief, MS Section
Director, MS Center
Associate Professor of Neurology
Perelman School of Medicine
University of Pennsylvania
Philadelphia, PA

Clyde E. Markowitz, MD is Director of the MS Center at the Hospital of the University of Pennsylvania, and is an Associate Professor of Neurology at the Perelman School of Medicine at the University of Pennsylvania in Philadelphia. He earned his medical doctorate from the Columbia University College of Physicians and Surgeons. He also completed a residency, postdoctoral research, and clinical fellowship at the Neurological Institute at Columbia University College of Physicians and Surgeons in New York.

His expertise is in the field of multiple sclerosis and he is involved in many clinical trials developing new compounds for the treatment of MS. Dr. Markowitz’s research interests include utilization of new MRI techniques to study the pathogenesis of MS, vision outcome measures in MS, and immunology of MS. He has held the position of Chairman of the Clinical Advisory Committee for the Delaware Valley Chapter of the National Multiple Sclerosis Society and is the author or co-author of a number of publications. He serves as an ad hoc reviewer for Multiple Sclerosis, Annals of Neurology, Archives of Neurology, Journal of the Neurological Sciences, Neuro-Rehabilitation, Neural Repair, Journal of Clinical Immunology, and The Consultant. Dr. Markowitz is a member of the American Academy of Neurology and he is certified by the National Board of Medical Examiners and the American Board of Psychiatry and Neurology. His work has been published several times in journals, such as Annals of Neurology and Neurology.

Jointly provided by Potomac Center for Medical Education and Rockpointe

This activity is supported by an educational grant from Biogen, Genentech, and Novartis Pharmaceuticals Corporation.

©2016 Rockpointe