New Challenges and Best Practices in Liver & Kidney Transplantation

A series of Live Grand Rounds Programs and an on-demand CME/CE-certified Webcourse

Welcome to "New Challenges and Best Practices in Liver & Kidney Transplantation".

A series of live CME/CE-certified programs will be presented at selected hospitals throughout the U.S. during 2013/2014, and a CME/CE-certified on-demand webcourse will be available in early 2014.

Program Description:

The Potomac Center for Medical Education and Rockpointe welcome you to New Challenges and Best Practices in Liver & Kidney Transplantation, a CME/CE-certified program designed to give medical professionals the latest news and information on the management of liver and kidney transplantation.

Controversies surrounding the increased number of simultaneous kidney-liver transplantations, along with an exponential increase in the understanding of the mechanisms underlying long-term graft rejection and loss, have placed the transplant care team on the verge of a paradigm shift in the management of solid organ transplantations.

Through an in-depth case discussion, this highly interactive CME/CE activity will explore the most contemporary issues in kidney and combined kidney/liver transplantation. Participants will review evolving algorithms that are guiding the selection of patients for liver transplant alone vs simultaneous kidney/liver transplant, as well as strategies for preventing and treating antibody-mediated rejection (AMR). By incorporating best practices and immunosuppression protocols and formulations, the transplant team will be able to deliver safer, more individualized regimens and achieve balance between rejection prevention and minimization of immunosuppressant-associated toxicity, while optimizing patient adherence.

Target Audience:

This CME/CE-certified initiative is intended for transplant physicians, transplant surgeons, nurses, pharmacists, and other members of the transplant team.

Accreditation Statements:

Physicians - This activity has been planned and implemented in accordance with the Essential Areas and policies of the Accreditation Council for Continuing Medical Education through the joint sponsorship of Potomac Center for Medical Education and Rockpointe. The Potomac Center for Medical Education is accredited by the ACCME to provide continuing medical education for physicians.

Nurses - Global Education Group is accredited as a provider of continuing nursing education by the American Nurses Credentialing Center's Commission on Accreditation.

Designation Statements:

Physicians - The Potomac Center for Medical Education designates this live activity for a maximum of 1.0 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity. For information about the accreditation of this program, please email

Nurses - This educational activity for 1.0 contact hours is provided by Global Education Group. Nurses should claim only the credit commensurate with the extent of their participation in the activity. For information about the nursing accreditation of this program, please contact Global at or 303-395-1782.

Calendars of Live Activities

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Visiting Professor Series

Related Online Offerings

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This program also has an associated webcourse. Click here to visit the on-demand CME/CE-certified activity.

Live Program Materials for Speakers and Administrators

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I. Administrator Material

II. Speaker Material

Audio Orientation

Thank you for joining us as an expert speaker for the 2013-14 Visiting Professor Series, "New Challenges and Best Practices in Liver & Kidney Transplantation."

This orientation will familiarize you with the complete slide set, provide insight from the program steering committee, and address potential questions. The following key topics will be discussed:

  • Analyze the most recent data on kidney and dual kidney/liver transplant outcomes, and identify criteria that are currently being investigated to guide patient selection for dual vs single organ transplant
  • Apply an up-to-date understanding of the mechanisms underlying antibody-mediated rejection to the initiation of evidence-based approaches to prevent rejection and minimize immunosuppressant-associated toxicity
  • Identify strategies to maximize adherence in patients undergoing solid organ transplant

Transcript of Speaker Orientation Download (PDF)

Audio download of Speaker Orientation

Audio Download

CME/CE-certified Program Slides

This version of the program slides has been CME/CE-certified and these slides are to be used for this activity. Download (PowerPoint)

Disclosure Information:

Potomac Center for Medical Education (PCME) adheres to the policies and guidelines, including the Standards for Commercial Support, set forth to providers by the Accreditation Council for Continuing Medical Education (ACCME) and all other professional organizations, as applicable, stating those activities where continuing education credits are awarded must be balanced, independent, objective, and scientifically rigorous.

All persons in a position to control the content of a continuing medical education program sponsored by PCME are required to disclose any relevant financial relationships with any commercial interest to PCME as well as to learners. All conflicts are identified and resolved by PCME in accordance with the Standards for Commercial Support in advance of delivery of the activity to learners.

The content of this activity was vetted by an external medical reviewer to assure objectivity and that the activity is free of commercial bias.

FDA Disclosure:

The contents of some CME/CE activities may contain discussions of non-approved or off-label uses of some agents mentioned. Please consult the prescribing information or full disclosure of approved uses.

Steering Committee

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Professor of Clinical Medicine
University of California
San Francisco, CA

Flavio Vincenti, MD completed his medical training, internship, and residency at the American University Medical Center in Beirut, Lebanon. He then completed a two-year nephrology fellowship at Emory University School of Medicine. He came to the University of California, San Francisco in July of 1975 for a transplant nephrology fellowship and has been on the staff of the Kidney Transplant Service at UCSF since 1976. He is board-certified in internal medicine and nephrology. Dr. Vincenti is a member of the Steering Committee of the Immune Tolerance Network, has been an Associate Editor of Clinical Journal of the American Society of Nephrology and the American Journal of Transplantation, and is on the Editorial Board of Transplantation.

Dr. Vincenti is widely published and has authored or co-authored more than 170 articles on transplantation. He was the primary investigator of an article published in 1978 in the New England Journal of Medicine concerning the important role of blood transfusions in improving outcomes following kidney transplantation. He also reported a series of articles on the complications of transplantation, including of aseptic necrosis and recurrent diseases in renal allografts. He has contributed to the understanding of the incidence and risk of recurrence of focal glomerulosclerosis, as well as its outcome after transplantation. In the 1990s, Dr. Vincenti participated in a number of important multicenter clinical trials including studies with tacrolimus, daclizumab, basiliximab, HuM291, anti-CD80/86 monoclonal antibodies, efalizumab, anti-CD154, tasocitinib and belatacept.

Dr. Vincenti was honored by the National Kidney Foundation of Northern California in 2000 for his contributions to transplantation and treatment of renal failure. He was the recipient of the AST 2002 Novartis Clinical Science Award, and was awarded the Lifetime Achievement Award in transplantation in 2012 by the American Society of Transplantation. Dr. Vincenti has been an active member of the American Society of Transplantation and helped establish the Clinical Trials Committee, which he chaired from 2002-2004; he then chaired the Development Committee from 2004-2006. He has been on the board of the American Society of Transplantation since 2003 and has served as its President (2007-2008).

Professor of Medicine
University of Pennsylvania Perelman School of Medicine
Medical Director, Kidney Transplant Program
Penn Transplant Institute
Philadelphia, PA

Roy D. Bloom, MD received his medical doctorate from the University of Witwatersrand in Johannesburg, South Africa. After postgraduate training in London, he completed a medical residency at Albert Einstein Medical Center in Philadelphia, PA. He completed nephrology fellowship training at the Brigham and Women's Hospital, as well as the Hospital of the University of Pennsylvania, from which he graduated in 1994.

Dr. Bloom initially joined the Division of Nephrology at Albert Einstein Medical Center, where he was appointed Medical Director of the Kidney Transplant Program. He then briefly served as Medical Director of the Kidney Transplant Program at Allegheny University of the Health Sciences/Hahnemann Hospital in Philadelphia. Since 1999, he has been a faculty member of the Renal Electrolyte and Hypertension Division at the University of Pennsylvania, where he is now a Professor of Medicine. He has been the Medical Director of the Penn Transplant Institute Kidney and Pancreas Transplant Program since 2002.

Dr. Bloom is a member of the International Society of Nephrology, the American Society of Nephrology, and the American Society of Transplantation. He has chaired both the Patient Care and Education Committee and the Clinical Trials Advisory Council of the American Society of Transplantation. At present, he serves on the American Society of Nephrology's Postgraduate Education Committee; concomitant with being a member of the Society's Transplant Advisory Group. He also co-chairs the American Society of Nephrology/American Society of Transplantation Joint Committee that is developing the Transplant Nephrology Practice Improvement Module for use in the American Board of Internal Medicine Maintenance of Certification Program. He has served on KDIGO Work Groups related to the development of clinical practice guidelines for both managing hepatitis C virus in kidney disease, as well as for the management of kidney transplant recipients.

Dr Bloom has served on program committees for the American Transplant Congress and has organized transplant-related symposia at the American Diabetes Association Annual Meeting. He co-chairs the Early Program on Transplantation at the annual American Society of Nephrology Kidney Week. He is the author of more than 100 publications and, in 2005, received the American Society of Transplantation Wyeth Clinical Science Career Development Award. His current research interests include clinical trials with contemporary and emerging immunosuppressive therapies and transplant outcomes related to patient comorbidities and complications.

Director of Nephrology
Hennepin County Medical Center
Professor of Medicine, University of Minnesota
Minneapolis, MN

Bertram L Kasiske, MD, FACP did his undergraduate training at Michigan State University, East Lansing, MI. He received his medical doctorate from the University of Iowa in Iowa City, IA. He then completed an internal medicine residency and fellowship training in nephrology at Hennepin County Medical Center, an affiliate hospital of the University of Minnesota in Minneapolis. He is the former Deputy Director of the United States Renal Data System and former Editor-in-Chief of the American Journal of Kidney Diseases.

Dr. Kasiske is Director of Nephrology at Hennepin County Medical Center and Professor of Medicine at the University of Minnesota. He is the Principal Investigator for a National Institutes of Health grant to study long-term effects of kidney donation and cardiovascular disease in kidney transplant recipients, and serves as the US Investigator for the Study of Heart and Renal Protection (SHARP). He is Co-director of Kidney Disease Improving Global Outcomes (KDIGO) and Director of the Scientific Registry of Transplant Recipients (SRTR) in the US.

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